Wytheville is a city in Southwest Virginia.

Get in

Wytheville is located at the intersection of two interstate highways. I-77 and I-81 provide access from the neighboring states of North Carolina, Tennessee, and West Virginia. I-81 also connects Wytheville to the larger metro areas of Northern Virginia.

By bus

• 1 Greyhound, 926 Max Meadows Rd. 

Sleep

• 1 Comfort Inn, 2594 East Lee Hwy, ☏ +1 276 637-4281. 
• 2 Comfort Inn, 315 Holston Rd, ☏ +1 276 228-4488. 
• 3 Comfort Suites, 695 Peppers Ferry Rd, ☏ +1 276 228-1234. 
• 4 Econo Lodge, 280 Lithia Rd, ☏ +1 276 228-5525. 
• 5 Quality Inn & Suites, 2015 E Main St, ☏ +1 276 228-4241. 
• 6 Ramada Wytheville, 955 Peppers Ferry Rd., ☏ +1 276 228-6000. 
• 7 Sleep Inn, 135 Nye Circle, ☏ +1 276 625-0667. 
• 8 Super 8, 130 Nye Circle (I-77 exit 41), ☏ +1 276 228-6620. Low cost no frills hotel offering a continental breakfast and free wifi. 

Go next

Routes through Wytheville

Charleston ← Bluefield ←	N  S	→ Jct E → Union Grove → Charlotte
Roanoke ← Radford ←	N  S	→ Bristol → Kingsport
Huntington ← Bluefield ←	NW  SE	→ Mount Airy → Winston-Salem