- Chamber of Commerce, 130 West Main Street, ☏ .
State Route 800 runs through the town north and south. It connects to Interstate 70 six miles north of the town. State Route 147 runs roughly east and west through the town.
There is no public transportation. Driving or walking across Barnesville is quick and easy.
- Dickinson Cattle Company, 35500 Muskrat Road (Located on State Route 800 north of Barnesville, between the village and Interstate 70), ☏ . M-Sa 10AM-5PM, Sunday 1PM-6PM during the summer. A 4,500 acre ranch built on reclaimed strip mine. Home of up to 1,500 registered Dutch buelingo, Texas longhorn, and African watusi cattle. Tour covers history of horned cattle in Ohio, Johnny Appleseed, Hopalong Cassidy, Ohio governor Wilson Shannon, and Hanging Judge Isaac Parker. See cattle being trailed and branded on this working cattle ranch. $10 adults, $4 children 4-12, free under 4.
- Barnesville Baltimore & Ohio Railroad Depot, 300 East Church Street. On site is the depot building, caboose #C-1974, and just down the walking trail is the railroad tunnel.
- 1 Barnesville Petroglyph.
- 1 Barnesville Pumpkin Festival (Located in downtown Barnesville), ☏ . Th-Su, last full weekend in September. Local festival that began in 1964 and now attracts more than 100,000 people annually. Pumpkin growers compete to grow the heaviest pumpkin each year, crowned the King Pumpkin. (Current record was set in 2007 and weighed in at 1,289 1/2 pounds.) Other attractions at the festival include an Antique & classic car show, crafts, new and antique farm machinery, live music on multiple stages, and contests for hog calling, tall tales, and tobacco spitting. The event reaches its peak attendance on Saturday for the Giant Pumpkin Parade. Free for most of the festival, $1 or less for craft displays.
- 2 [dead link] Victorian Mansion Museum, 532 North Chestnut Street, ☏ . May 1 - October 1, W-Su 1PM-4PM. Fully restored, twenty-six room Romanesque style mansion. Sights include carved woodwork, moldings, mantels and doors, as well as 22k gold decorations, decorative locks, hinges and gas and electric lighting fixtures. Houses one of the largest collections of original clothing from the 1890s in Ohio. Annual Christmas tour runs from Thanksgiving to Christmas. $5 adults, $2 age 6-18.
- Watt Center for History and The Arts (Watt Center), 475 Watt Ave (Rt. 800 S., left at first light onto Church St. to Mulberry St. intersects with Watt Ave., turn left.), ☏ , . Open May-Sept by Appointment. The original office building of the Watt Car and Wheel Company. Exhibits including coal history, business, industry and agriculture. Donations appreciated.
- Barnesville Antique Mall, 202 North Chestnut Street, ☏ . Tu-Su. Three floors of tools, furniture, glass china, quilts, pottery including Roseville and Weller, primitives, etc.
- Bless Your Heart Folk Art, 157 East Main Street, ☏ . Quaint little store full of primitive and country decor, candles & diffusers, curtains, wallpaper, quilts, calendars, wooden signs, garlands, all occasion cards and other unique gifts.
- Avenues of Barnesville, 132 East Main Street, ☏ , ✉ email@example.com. Gifts, home decor, jewelry, cards, etc.
- [dead link] The Raven Pickers, 134 West Main Street, ☏ , ✉ firstname.lastname@example.org. 10 a.m. to 5 p.m from Monday to Friday, Saturday 10 to 4. Closed Sunday.. They sell antiques, vintage, mid century, and what they call "good junk".
- Antiques On The Main, 108 North Chestnut Street, ☏ .
- Paula' Primitives, 112 S Chestnut St, ☏ . They make and sell custom handmade crafts and primitive decor.
- Annie K's, 777 East Main Street, ☏ . Family owned, small town restaurant featuring home cooked meals. Hosts murder mysteries, comedy shows, and live bluegrass and other music.
- China One, 201 South Chestnut Street, ☏ .
- My Pizza Place, 123 East Main Street, ☏ .
- Home Pizza, West Main Street, ☏ .
- D & J's Pizza Parlor, 112 East Church Street, ☏ .
- Bob's Pizza and Sub Stop, 110 East South Street, ☏ . Pizza, subs, wings, onion rings, pepperoni rolls, calzones, etc. Alcohol and cigarettes can be purchased as well. They also deliver locally.
- Blue Moon Tavern, 126 W Main St, ☏ . Large selection of beer including 3 kinds on tap plus a full bar. Bar menu features wings. Jukebox/ATM. Periodic live music Opens daily at 5pm.
- Ed's Place, 787 East Main Street, ☏ .
- Harrison House Apartment, 501 East Main Street, ☏ , ✉ email@example.com. Features a private three-bedroom apartment with a private entrance. The recently remodeled apartment has a full kitchen and semi-private bath. You can choose from one or three fully furnished bedrooms with two queen sized beds and one double bed. All bedrooms have cable television and wireless internet.
- Sleep Inn & Suites - Belmont, 41371 Reco Road, Belmont, OH, ☏ .
- 1 WBNV (Barnesville-Woodsfield), 175 E Main St (93.5Mhz), ☏ . Barnesville's hometown radio station, a member of the AVC Communications Inc. family. Broadcasts Cleveland Indian baseball games and local high school football, basketball, and baseball for the Barnesville Shamrocks and Monroe Central Seminoles.
- Barnesville Enterprise, 166 East Main Street, ☏ , ✉ firstname.lastname@example.org. Weekly local newspaper covering western Belmont County, in operation for over 140 years. It is the oldest active, continuously operated business in the village.
- Barkcamp State Park: 125 Electrified campsites and featuring hot showers, picnic tables, and firerings. Pets allowed in designated areas. Swim, fish, boat, or hunt (in designated areas). 65330 Barkcamp Road, +1 740 484-4064
- Barnesville Memorial Park: Fish or boat on 12-acre Park Lake. Watch baseball or softball on one of three lit ball fields, one housing a covered grandstand. Lit horseshoe pit, basketball courts, tennis courts and volleyball court. Two walking trails that wind around Park Lake. Also home to the villages 4 July fireworks display.