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The Central Panama region includes much of Panama province and all of Colon and Cocle provinces.
- 1 El Valle - a charming little town nestled in the second biggest inhabited volcanic caldera in the world. El Valle boasts an all-year spring-like climate, amazing biodiversity, and a wide selection of hotels and restaurants among others. Located about an hour west of Panama City.
- 2 Contadora Island
- 3 Pearl Islands - Archipelago de las Perlas
- 4 Taboga - an island getaway close to Panama City