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The Republic of the Congo's Coast and Mayombe region is the country's second most populous after Pool, and is home to its second largest city at Pointe-Noire.
- 1 Madingo-Kayes
- 2 Pointe-Noire — the second largest city of the Republic of the Congo is a major sea port and a tourist destination
- 1 Conkouati Reserve — the most bio diverse park in the country and includes the only marine-protected area in Congo
- 2 Dimonika Biosphere Reserve — a reserve covering lowland rainforest and savanna
- 3 Tchimpounga Sanctuary — the largest chimpanzee sanctuary on the African continent