Castile-La Mancha or Castilla La Mancha is a region of central Spain where the fictional Don Quixote fought imaginary windmills. Those windmills can still be seen today. The climate of the region is desert-like, and the dialect of Spanish is very similar to the Spanish spoken in Madrid.
- Campillo de Ranas, a village some 66 km north of Guadalajara, notable for its gay Socialist mayor who pushed back on rural decline of villages like this by promoting it as a destination for non-religious weddings for both same-sex and mixed-sex couples.
The town of Almadén has long traditions of mercury mining and has been inscribed in the UNESCO World Heritage List as Heritage of Mercury Almadén and Idrija.