The I-380 Corridor (sometimes just "The Corridor") is a region in Eastern Iowa. In general, the expression is used to describe Linn and Johnson Counties, which are connected by I-380.
- Cedar Rapids: One of the two anchors of the region, it is Iowa's second largest city.
- Coralville: A suburb of Iowa City and home to the regional Coralville Mall.
- Hiawatha: A large suburb of Cedar Rapids.
- Iowa City: The second major anchor of the region, it is home to the University of Iowa.
- Marion: A large suburb of Cedar Rapids.
- Mount Vernon: A rural community and home to Cornell College.
- Lake McBride: A major man-made lake in northern Johnson County. Popular recreational area.
- Palisades-Kepler State Park: A state park on US 30 near Mount Vernon noted for its deep ravines, bluffs and natural beauty.
Like many other areas in the Midwest, the I-380 corridor's cities were settled due to their proximity to nearby rivers. Iowa City was the original capitol of the State.
The region is most closely associated with I-380, which connects the region to Waterloo. However, it is also accessible via I-80 (from the Quad Cities or Des Moines), US 151 (from the Amana Colonies or Dubuque) and US 30 (from Clinton or Ames).