Northwest Italy consists of four of Italy's regions: Piedmont, Liguria, Lombardy and Valle d'Aosta. To the east lies Northeast Italy, to the north is Switzerland and to the west France. The Italian Lake District is mostly in Northwest Italy.
- Aosta Valley – a small region in the Alps
- Liguria – the coastal region
- Lombardy – the eastern part of Northwest Italy
- Piedmont – the western region, containing most of Italy's border with France
- Bergamo – a fairytale pastel-coloured city perched atop a hillside, and the gate to Bergamo Alps.
- Brescia – a major industrial powerhouse since the Ancient Roman times, and a UNESCO World Heritage Site.
- La Spezia
- Mantua (Italian: Mantova) – the Ducal Palace has a cycle of frescoes by Mantegna that no art lover should miss. This city is also an UNESCO World Heritage Site.
- Milan (Italian: Milano) – shares with Paris the title of fashion capital of the world, and is Italy's second city and the main Italian economic centre.
- San Remo
- Turin (Italian: Torino) – After the Italian unification, on 17th March 1861, Turin was the first capital of modern Italy.
- The Sacri Monti of Piedmont and Lombardy – a UNESCO World Heritage site consisting of nine groups of holy mountains featuring chapels and other Christian religious sites.