Río Verde Valley (Region Medio) is in San Luis Potosí.
- 1 Rioverde and 2 Ciudad Fernández – The capitals of their respective municipalities, these two towns are separated only by a street and form the largest town in the region.
- 3 Cárdenas
- 4 Cerritos
- 5 Ciudad del Maíz
- 6 El Refugio
Protected natural areas
- Reserva de Tancojol
- Reserva Forestal Nacional Porción Boscosa del Estado de San Luis Potosí
- Reserva de la Biosfera Sierra El Abra Tanchipa
The Sierra Madre Oriental separates the Río Verde Valley and the Huasteca Potosina. Several mountain ranges to the west separate the Río Verde Valley from the Central Plateau (Altiplano). The region has extensive valleys between these mountain ranges that boast very fertile soil.
The vegetation includes oak, pine, popular and walnut trees. Some areas are volcanic along with the limestone of the Huasteca Potosina.
The main native group in this region is the Pames who still maintain their culture and language.