- 1 Barra de Valizas
- 2 Cabo Polonio - beach hippie community with dope, dreadlocks and not much else
- 3 Chuy - border crossing town with Brazil
- 4 La Paloma
- 5 Maldonado - the capital of the eponymous department
- 6 Piriapolis
- 7 Punta del Diablo - sleepy old fishing village much beloved by the dreadlocked
- 8 Punta del Este - world famous beach party town
- 9 Rocha
- 10 San Carlos - including an old church that was built in colonial times
Punta del Este Airport (PDP IATA) is in Maldonado and has a few commercial flights, mainly from Buenos Aires (AEP IATA). The other option is to fly into Montevideo (MVD IATA); intercity buses from Montevideo to this region generally stop at the airport to pick up passengers.
International buses to Punta del Este are available from Porto Alegre and Florianópolis, Brazil. You can also take a bus to the border town of Chuí, walk across the border to Chuy, and take a bus from there.
Cruise ships and yachts can dock at Punta del Este.
Depending on where you're trying to go, you might have direct buses multiple times a day or you might find yourself having to transfer on a route that doesn't run frequently. Maldonado/Punta del Este and Rocha are probably the most important hubs. At worst, you can always head back to Montevideo, which has service everywhere, but if you're trying to get from one Rocha Department beach town to another, going all the way to Montevideo will add a lot of unnecessary hours to the trip.
This is generally a safe region—Brazilians come here on vacation to relax on the beach without the risk of crime they'd have to worry about at home. But watch out for pickpockets and petty thieves at the beach resorts, especially Punta del Este.