Cayo Largo is an island in Cuba.
Jeep rentals are easy and cheap. Although there isn't much to view around the island, if you have a true desire for absolute privacy it is easy to get to the north east end of the island for complete seclusion. Depending on the time of year there are complimentary shuttles from the hotels to the beach Playa Serena, at other times there is a minimal fee involved. Typically the bus transport to/from the airport is included with the vacation packages.