There are airports in Palu (PLW IATA) (for Lake Poso and the central highlands), and Luwuk (LUW IATA) (for the Togian Islands, Morowhali), with a reasonable amount of domestic departues from Manado and Makassar.
From the south: buses leave Rantepao in Tana Toraja everyday around 09:00 (delays can be common), and stops at Tentena, Poso and Palu. The road is in a bad condition, with potholes being quite common. Therefore heavy delays can be expected. Try to get a seat on the more comfortable executive bus for this reason.
From the north: an overland bus route goes to Manado by Toli-Toli and Gorontalo, this is not very used by tourists though, as the Togian Islands is omitted on this route.
Small ferries arrives in Ampana from Wakai, the "capital" of the Togian Islands everyday apart from Sunday and Thursday. The 5-hour trip is not recommended for people prone to seasickness, but the scenery is very nice.
Standard Indonesian fare in the warungs, very few "proper restaurants". The fish, and especially the Eel from Lake Poso can be delicious.
Bat: at least several warungs in Tentena, down by Lake Poso, sells this local delicacy. It is extremely spicy, and quite bony, but must be tried.
As of 2017, the East Indonesia Mujahideen was continuing to launch attacks in the central town of Poso. Tourists are not targeted, but there are very few visitors in the area anyway and the police and military presence is very heavy.