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North America > United States of America > Midwest > Missouri > Northeast Missouri > Hannibal


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Hannibal is a city in Missouri. It is located approximately 100 miles northwest of St. Louis and is located on the west bank of the Mississippi River.

Hannibal is best known as the boyhood home of author Samuel Longhorn Clemens, more commonly known as Mark Twain. Twain's The Adventures of Tom Sawyer and Adventures of Huckleberry Finn are set in Hannibal. Many historical sites in the city revolve around Twain and his writings, which occupy a prominent place in the history of the Underground Railroad era.


Get in[edit]

By car[edit]

From the south: U.S. Route 69 or U.S. Route 71.

From the west: U.S. route 36

From the east: Interstate 72

From the north: U.S. Routes 61/24

By bus[edit]

Burlington Trailways operates daily buses in each direction between St. Louis and places in Iowa, stopping in Hannibal.

By plane[edit]

American Airlines partner Cape Air operate flights from St. Louis to nearby (28 miles away) Quincy, Illinois.

Get around[edit]







  • Garth Woodside Mansion (Hannibal Bed And Breakfast), 11069 New London Road, toll-free: +1-888-427-8409. A bed and breakfast and restaurant in a beautiful mansion where Mark Twain himself stayed.


Go next[edit]

Travelers interested in the creative works of Mark Twain might also head west along U.S. Route 36 to Marceline, childhood home of another creative genius, Walt Disney.

Routes through Hannibal
St. JosephMarcelineI-72.svg ends ←  W I-72.svgUS 36.svg E  → Junction I-172.svg to QuincyJacksonvilleSpringfield
BurlingtonFort Madison ← Junction W US 24.svg E  N US 61.svg S  Bowling GreenSt. Louis

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