Salamanca is part of the Allegany reservation.
You may take Old State Route 17 in from Red House, Interstate 86 from Jamestown, and several other highways in and around.
The nearest airport with scheduled flights is Bradford Regional Airport (BFD IATA) in Bradford, Pennsylvania, which is served with daily commuter flights from Pittsburgh via Southern Airways Express: four on weekdays, two on Saturdays, and three on Sundays. In practice, however, arriving in Salamanca by plane usually means flying into Buffalo Niagara International Airport.
- Coach USA buses arrive and depart from the corner of Central and Linden Avenues, in front of the Corner Deli.
- Fullington Trailways buses arrive and depart from the Dudley Hotel at 132 Main Street.
- Service from DuBois via St. Marys, Bradford, and various points in between.
- Service from Buffalo via Springville, Ellicottville, and various points in between.
- 1 Salamanca Rail Museum, 170 N. Main St., ☏ . Tu, Th & Sa 10AM-4PM. It's no stretch to say that Salamanca would not exist today but for the railroads. The low-lying swampland on which the city was built was useless to the Seneca but vital as a transportation link through the hilly terrain of the local area, and by the turn of the century there were no fewer than three lines — the Erie, the Pennsylvania, and the Buffalo, Rochester & Pittsburgh — passing through town, by which tens of thousands of bundles of wood from the thick forests of southern Cattaraugus County were shipped every day to lumber markets nationwide. Today, the handsome old BR&P depot has been fully restored and reopened as a museum detailing Salamanca's railroad history through historic artifacts, old photos, and engaging video presentations. Donation.
- 2 Seneca Iroquois National Museum (Onöhsagwë:de' Cultural Center), 82 W. Hetzel St., ☏ . Tu-Sa 9AM-5PM. The Seneca Iroquois National Museum trends more toward the dry/educational end of the spectrum than the engaging/entertaining, but if you have a more-than-passive scholarly interest in Seneca history, ethnology, religion, art, handicrafts, traditional medicine, etc. etc. ad nauseam, this museum's vast collection covers all those topics exhaustively. A special emphasis is placed on the 1965 construction of the Kinzua Dam downriver in Pennsylvania (more on that later), a tragic chapter in Seneca history whereby 10,000 acres (4,000 ha) of tribal land, including some of the most fertile farmland and important cultural sites on the reservation, were condemned and are now under the water of the Allegheny Reservoir. Outdoors there's an amphitheater where traditional cultural performances of various types are hosted. $9.50; seniors, students and military veterans $6; children 7-17 $5.25, children 6 and under free.
- The Crosspatch, 5281 Baker Rd., ☏ .
- Hampshire Mills, 890 Broad St (Route 417 at Old Route 17 (Red House Road)), ☏ . 10AM-6PM. General store, since 1960s.
- Langworthy Restaurant, 6661 NY-417, ☏ .
- Myers Steak House, 460 Wildwood Ave, ☏ . 11:30AM-10PM.
- [dead link] Paradise Club, 4250 N State St, ☏ . 6PM-2AM. This is a nightclub.
- 1 Seneca Allegany Casino & Hotel, 777 Seneca Allegany Blvd (South of I-86 on Route 417.), toll-free: . $105 per night.
- Holiday Inn Express & Suites, 779 Broad St, ☏ . $109 per night.
- Pyramid Inn, Hardscrabble Rd & U.S. BUS 219, ☏ . Known for having, "the best wings in the Salamanca area"
|Routes through Salamanca|
|Jamestown ← Randolph ←||W E||→ Olean → Elmira|
|Buffalo ← Ellicottville ← Jct N ←||N S||→ Bradford → DuBois|
|Buffalo ← Little Valley ←||N S||→ Bradford → DuBois|