- For the region in Maine, see Greater Portland.
- Aloha - a census designated place wedged between Beaverton and Hillsboro. Residents here have always resisted annexation to either Beaverton or Hillsboro
- Beaverton - suburb 7mi/11km west of Portland growing up to become an economic powerhouse as it is home for Columbia Sportswear, Electro Scientific Industries, Nike & Tektronix.
- Forest Grove
- Hillsboro - county seat for Washington County, one of three counties making up the greater Portland metropolitan area and also a location for one of several Intel pre-fab plants.
- Lake Oswego
- Oregon City
- West Linn
As well as Portland, the city proper, the area includes:
- East Multnomah County - the eastern suburbs of the city, including the cities of Gresham and Troutdale; the gateway to Mount Hood and the Columbia River Gorge.
- Washington County (Oregon) - the western suburbs of Portland, a growing high-tech area near Hillsboro and Beaverton, and home to Nike and other well-known Oregon companies. The rural areas also have wineries.
- Clackamas County - the southern and southeastern suburbs, including affluent Lake Oswego and historic Oregon City, leading to the foothills of Mount Hood.
Two main highways pass east-west through the region - Interstate 84 and U.S. Route 26 (Powell Boulevard). I-84 going east will take you into the Columbia Gorge, while U.S. 26 going east takes you up Mount Hood and into Central Oregon.
- Oregon Route 217 is another freeway that runs from Tigard to Beaverton.
The MAX Blue Line runs from downtown Portland into Gresham, terminating at the Cleveland Avenue station.
- Vancouver (WA), is sometimes included in the region even though it is across the Columbia River in Washington.